Microheterogeneity on Enzyme: Formation, Analysis and Effects of Structural Variants
Time: 11:40 am
day: Conference Day Two
Details:
- Understanding common mechanisms that lead to microheterogeneity, such as post-translational modifications (PTMs), degradation and modifications by reactive metabolites and excipients
- Recognizing why microheterogeneity often goes undetected and learning analytical strategies to accurately assess protein quality
- Discussing strategies to improve the success of enzyme engineering efforts by controlling microheterogeneity
