Enabling Biocatalysis Through Next-Generation DNA Synthesis
Time: 2:30 pm
day: Day One
Details:
• Finding a good starting enzyme backbone has the potential to simplify and accelerate the workflow for biocatalysis optimization
• However, the cost of DNA synthesis can significantly limit the sequence space for enzyme backbones that can serve as a starting point in enzyme engineering
• Here, we present novel synthesis methods and screening products that have the potential to increase the breadth of “WT” starting points by up to 1000X
